Our dossier no 22 presents the challenges confronting popular movements in Latin America and the Caribbean in the face of a new advance of imperialism, the right-wing, and neoliberal projects in the region. These policies have grave consequences for the people and have corroded the legitimacy of the governments that propel them forward, developing new processes of popular struggle, mobilizations, uprisings, protests, and resistances. In this context, it is necessary for Latin American critical thought to reflect on the methods and capacity to promote an alternative anti-neoliberal, anti-racist, anti-patriarchal, anti-capitalist subjectivity.